We envision a future where AI-powered smart cities and intelligent industries create harmonious, efficient, and sustainable environments that improve quality of life while driving economic prosperity. Through this symposium, we aim to accelerate the digital transformation of urban infrastructure and manufacturing systems, ensuring that technological innovations serve the needs of citizens and workers while promoting environmental sustainability, social equity, and economic competitiveness. Our vision encompasses cities where data-driven insights optimize everything from traffic flow to energy consumption, and factories where intelligent systems enhance productivity, safety, and adaptability.